|
|
Proprietary ligands for asymmetric hydrogenation |
 |
| Substrate |
Hydrogenation with SYNPHOS® (ee %) |
Hydrogenation with DIFLUROPHOS®
(ee %) |
 |
- |
97 % |
 |
94 % |
36 % |
 |
99 % + |
- |
 |
63 % |
81 % |
|
DIFLUORPHOS |
 |
|
SYNPHOS |
 |
|
Publications
|
 |
SYNPHOS®, a new chiral diphosphine ligand, Sébastien Duprat de Paule, Séverine Jeulin, Virginie Ratovelomanana-Vidal, Jean-Pierre Genêt, Nicolas Champion and Philippe Dellis, Tetrahedron Letters 44 (2003), 823 |
|
|
|